Children aged two, three and four years old in the Skegness area will be offered the single dose nasal spray flu vaccine, Fluenz Tetra.
The needle-free vaccine is an alternative to the traditional injectable flu vaccine, which will continue to be offered to those aged 65 and over, pregnant women, carers and adults and babies with a long-term medical condition.
The Fluenz immunisation is a simple, painless nasal spray.
Earlier this yeat ome secondary school children have been offered the vaccine as part of a pilot scheme in selected schools nationwide.
It is now being rolled out across Lincolnshire for the younger children.