Resurfacing works will be carried out on South Road between the Sea Road and Sunningdale Drive junctions in Chapel St Leonards.
The scheme is due to start at 7am on Wednesday November 4, and is expected to last for three days.
A signed diversion route will be in place throughout the works. Access for residents and businesses will be maintained, although there may be minor delays and motorists should allow extra time for their journey. Residents and businesses have already received written notification and information signs will be in place before the scheme starts.