The Conservative Party has started the search to find a replacement candidate for outgoing MP Mark Simmonds.
Mr Simmonds had already been selected by the party to defend his seat, which he won with a 12,426 majority in 2010.
But Mr Simmonds announced he will stand down in May after quitting the Government.
A spokesman for the Boston and Skegness branch told The Standard that applications opened last week – with members expected to make their choice from the contenders in about three weeks.
It is understood that former Lincolnshire County Council finance portfolio holder Kelly Smith may be one of the candidates.