Four people were injured when a car crashed on the A158 at Wragby on Friday.
The collision, shortly after 3pm, involved the four occupants of a silver Mazda Takuya.
The two most seriously injured, a woman aged 56 and a man aged 51, both from Barnsley, were passengers in the car. The man was airlifted to Hull Royal Infirmary and woman was taken to Lincoln County Hospital.
The driver, a 47 year-old man, and a 26 year-old male passenger, both also from Barnsley, were treated at LCH for less serious injuries.
The road was reopened around 6pm.
Anyone who witnessed the collision or who saw the vehicle before the incident should contact the Collision Witness Hotline on 01522 558855.