Network Rail is to suspend all rail services east of Sleaford after 4.30m today (Thursday) after the Environment Agency issued several severe flood warnings around the Boston area.
Severe flood warnings are only issued by the agency when it is thought there is a risk to life.
Hundreds of properties in Boston are also on stand-by for possible evacuation.
Explaining the decision to cancel all rail services between Sleaford and Skegness, Phil Verster, Route Managing Director for Network Rail, said: “The forecast predicts severe flooding along the east coast at high tide this evening.
“We have taken the decision to stop services in order to keep passengers and railway workers safe.
“Our teams are out before the predicted flood doing everything possible to protect the infrastructure.
“We will respond to any damaged caused by flood water as soon as it is safe to do so.
“An exceptionally high tide is also expected tomorrow morning. We will issue an update on services tomorrow as soon as the situation becomes clear.
“Services further north and on the mainline are till suffering from disruption following todays high winds.
“Our teams have removed around 20 fallen trees and numerous items which have blown on to lines today. We are in the process of checking routes and restoring services as quickly as it is safe to do so.
“I thank passengers for their patience as we work to minimise the impact of this extreme weather on our railway.”